Located in the rapidly evolving Tampa Heights corridor, 105 W Columbus Drive presents a rare opportunity to acquire a distinctive three-story commercial building with high visibility along W Columbus Drive, just minutes from Downtown Tampa’s central business district. Originally constructed in 1910 and renovated in 2015, the property blends historic character with modern functionality. The ±3,350 square foot building features a flexible and efficient layout, including an open first level ideal for a reception area, client-facing lobby, or collaborative workstations, with private offices and suites distributed across the upper floors. The building offers multiple private offices with ensuite or adjacent full bathrooms, including a spacious second-level suite with a luxury bath and an expansive balcony overlooking the Downtown Tampa skyline. The third level features a private suite with a full bathroom, providing additional flexibility for executive office use, private workspace, or optional residential accommodations. The property is well-suited for an owner-user seeking a centralized headquarters location, ideal for uses such as a law firm, insurance agency, consulting firm, real estate office, architecture or design studio, or other professional service providers. Alternatively, the layout supports a multi-tenant configuration, allowing for individual office or suite leasing. The property includes on-site parking, with a paved driveway along the west side and additional parking along the east side accessible via a side alley. The property benefits from strong daily traffic along W Columbus Drive, providing excellent visibility and exposure for signage and business presence. Zoned CG (General Commercial), the property allows for a wide range of office, service, and commercial uses. The Future Land Use designation supports continued mixed-use and urban development, reinforcing the long-term growth potential of the site. Strategically positioned within Tampa Heights, the property is surrounded by significant public and private investment and lies within one of Tampa’s most active redevelopment corridors. Nearby transformative projects include Gas Worx, which is reconnecting Downtown Tampa and Ybor City, as well as the planned East Ybor redevelopment led by Darryl Shaw, expected to include a future campus for Tampa General Hospital. The property also benefits from close proximity to Armature Works, the Tampa Riverwalk, and the Downtown Tampa business district, placing it within minutes of key employment, dining, and lifestyle destinations. The property is located within a designated Opportunity Zone, offering potential tax advantages for qualified investors. With high visibility, flexible office layout, on-site parking, and proximity to major redevelopment projects, 105 W Columbus Drive represents a compelling opportunity for both owner-users and investors seeking a presence in one of Tampa’s most dynamic urban growth corridors.